The AEG-1/MTDH-Specific antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to Metadherin, and MTDH. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The AEG-1/MTDH-Specific antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH